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Report: Merck Tried to Bury Vioxx Concerns for Years Re: Report: Merck Tried to Bury Vioxx Concerns for Years -- Posted by George Verak on 11-29-04 09:41
FYI
http://www.vioxxlitigator.us
rbystrianyk@gmail.com (Roman Bystrianyk) wrote in message news:<4f28e591.0411010902.582d609e@posting.google.com>... > http://www.healthsentinel.com/news.php?event=news_print_list_item&id=364
>
> "Report: Merck Tried to Bury Vioxx Concerns for Years", Reuters,
> November 1, 2004,
> Link: http://www.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6675039
>
> Internal e-mails and other documents from Merck & Co. show the company
> fought for years to keep safety concerns from undermining the drug's
> commercial prospects, the Wall Street Journal reported on Monday.
>
> Vioxx, a drug known as a COX-2 inhibitor, was withdrawn from the
> market after it was shown to double the risk of heart attack and
> stroke in patients who had been taking it for at least 18 months.
> Vioxx generated some $2.5 billion in annual sales, and its withdrawal
> pummeled Merck's shares.
>
> On Monday, the Journal reported that an e-mail dated March 9, 2000,
> suggested Merck recognized that something in Vioxx was linked to
> increased heart risk.
>
> Edward Scolnick, Merck research chief at the time, wrote in the e-mail
> that cardiovascular events "are clearly there" and called it a
> "shame."
>
> Although Scolnick compared Vioxx with other drugs with known side
> effects and wrote, "there is always a hazard," the company's public
> statements continued to reject the link between Vioxx and increased
> intrinsic risk.
>
> Ted Mayer, a lawyer representing Merck, told the journal that the
> e-mails and marketing materials were "taken out of context" and "do
> not accurately represent the conduct of Merck and its employees."
>
> But a memorandum dated Nov. 21, 1996, by a Merck official illustrated
> that the company wrestled with Vioxx's potential to induce a cardiac
> event, the report said. Another e-mail highlighted the possibility
> that patients could suffer blood clots unless they were also given
> aspirin.
>
> Those documents may be used in ongoing litigation against the company.
>
> On Friday, Merck -- citing documents that had been made public --
> issued a statement saying that it acted "responsibly and
> appropriately" in developing and marketing Vioxx.
>
> It was not immediately clear if it was referring to those obtained by
> the Journal, and a company representative was not immediately
> available to comment early Monday.
FYI
http://www.vioxxlitigator.us
Re: Report: Merck Tried to Bury Vioxx Concerns for Years -- Posted by awthrawthr on 11-30-04 22:06
rbystrianyk@gmail.com (Roman Bystrianyk) wrote in message news:<4f28e591.0411010902.582d609e@posting.google.com>...
Today, I just purchased a product called "Zyflamend" made by
"NewChapter" and probably widely available at independent health food
stores. It advertises itself as a natural COX-2 inhibitor. It also
notes that it doesn't interfere with the COX-1 cycles (that is what
causes some of the serious side effects of drugs such as Vioxx,
Celebrex, Bextra, etc.)
I bought the Zyflamend because it contains several herbal extracts
that I respect. It will be interesting to me to see how or if it
works.
I've used a liquid made by Vitamin World that has worked well (Liquid
Maintenance), but I like to try different products. Also the Zyflamend
ingredients might have more general benefits, such as prostate
support.
I'll keep you posted, especially if it makes me taller or more
handsome.
_________________________
Visit http://www.itsnotjustforsex.com
> http://www.healthsentinel.com/news.php?event=news_print_list_item&id=364
>
> "Report: Merck Tried to Bury Vioxx Concerns for Years", Reuters,
> November 1, 2004,
> Link: http://www.reuters.com/newsArticle.jhtml?type=healthNews&storyID=6675039
>
> Internal e-mails and other documents from Merck & Co. show the company
> fought for years to keep safety concerns from undermining the drug's
> commercial prospects, the Wall Street Journal reported on Monday.
>
> Vioxx, a drug known as a COX-2 inhibitor, was withdrawn from the
> market after it was shown to double the risk of heart attack and
> stroke in patients who had been taking it for at least 18 months.
> Vioxx generated some $2.5 billion in annual sales, and its withdrawal
> pummeled Merck's shares.
>
> On Monday, the Journal reported that an e-mail dated March 9, 2000,
> suggested Merck recognized that something in Vioxx was linked to
> increased heart risk.
>
> Edward Scolnick, Merck research chief at the time, wrote in the e-mail
> that cardiovascular events "are clearly there" and called it a
> "shame."
>
> Although Scolnick compared Vioxx with other drugs with known side
> effects and wrote, "there is always a hazard," the company's public
> statements continued to reject the link between Vioxx and increased
> intrinsic risk.
>
> Ted Mayer, a lawyer representing Merck, told the journal that the
> e-mails and marketing materials were "taken out of context" and "do
> not accurately represent the conduct of Merck and its employees."
>
> But a memorandum dated Nov. 21, 1996, by a Merck official illustrated
> that the company wrestled with Vioxx's potential to induce a cardiac
> event, the report said. Another e-mail highlighted the possibility
> that patients could suffer blood clots unless they were also given
> aspirin.
>
> Those documents may be used in ongoing litigation against the company.
>
> On Friday, Merck -- citing documents that had been made public --
> issued a statement saying that it acted "responsibly and
> appropriately" in developing and marketing Vioxx.
>
> It was not immediately clear if it was referring to those obtained by
> the Journal, and a company representative was not immediately
> available to comment early Monday.
Re: Report: Merck Tried to Bury Vioxx Concerns for Years -- Posted by Katherine Wolfe on 12-03-04 19:17
"awthrawthr" wrote in message
news:f8602f93.0411302206.657e7fbe@posting.google.com... > rbystrianyk@gmail.com (Roman Bystrianyk) wrote in message
news:<4f28e591.0411010902.582d609e@posting.google.com>... >
> Today, I just purchased a product called "Zyflamend" made by
> "NewChapter" and probably widely available at independent health food
> stores. It advertises itself as a natural COX-2 inhibitor. It also
> notes that it doesn't interfere with the COX-1 cycles (that is what
> causes some of the serious side effects of drugs such as Vioxx,
> Celebrex, Bextra, etc.)
I've tried Zyflamend for chronic back pain, and it's a whole lot worse on my
stomach than any other anti-inflammatory I've ever taken. Bad enough where
when I take it with meals, and a glass of milk, I *still* feel like it's
chewing a hole through my stomach lining. I can't tell you whether it did
anything for inflammation, I couldn't take it long enough to find out!
Hope it works for you....
Katherine
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