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New and effective approach to anti-inflammatory therapy


New and effective approach to anti-inflammatory therapy -- Posted by doe on 11-23-04 23:26



By impounding iron, FHC foils cell suicide, fuels inflammation
12 Nov 2004

A research team based at the University of Chicago may have found a way to
manipulate cell suicide, also known as programmed cell death, a normal process
that regulates cell number but that goes awry in chronic inflammatory
disorders, cancer and other diseases.

In the 12 Nov. 2004 issue of the journal Cell, the scientists show that a key
step in the process of preventing cell suicide is the induction of ferritin
heavy chain (FHC), a protein that collects and hoards iron. By sequestering
iron -- which cells with suicidal tendencies need to make the harmful
substances that induce death -- FHC prevents cellular suicide.

http://tinyurl.com/4fj4c

Who loves ya.
Tom
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