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Still's disease / dramatic joint pain response


Still's disease / dramatic joint pain response -- Posted by doe on 12-12-04 09:34


Clin Exp Dermatol. 2004 Jul;29(4):410-2. Related Articles, Links


Improvement of adult Still's disease with granulocyte and monocyte adsorption
apheresis.

Kanekura T, Terasaki K, Higashi Y, Yoshii N, Kawahara K, Maruyama I, Kanzaki T.

Department of Dermatology, Kagoshima University Graduate School of Medical and
Dental Sciences, Japan. takurok@m2.kufm.kagoshima-u.ac.jp

Adult Still's disease is characterized by a high spiking fever, transient skin
rash, and polyarthralgia. Joint pain is one of the major complaints and is
often intractable. We assessed the efficacy of granulocyte and monocyte
adsorption apheresis (GCAP) therapy for treating arthralgia in adult Still's
disease. A 33-year-old woman with adult Still's disease who suffered from
recalcitrant arthralgia resistant to systemic corticosteroids was treated with
GCAP therapy. She underwent five GCAP treatments at 5-day intervals. Her joint
pain responded dramatically to the GCAP therapy, suggesting that GCAP may be
useful for treating adult Still's disease. We present a detailed description of
the patient and this novel therapy.

Publication Types:
Case Reports

PMID: 15245543 [PubMed - indexed for MEDLINE]

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