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Mother of young sufferer
Re: Mother of young sufferer -- Posted by ironjustice@aol.com on 05-02-05 00:50
If you look below .. iron .. seems to be a problem .. and if iron
supplements are a problem .. then .. logic .. tells you .. iron filings
added to every bit of floured product your child .. eats .. WILL ..
cause .. destruction ..
EXPERIMENTAL BIOLOGY UPDATE: Arthritic kids' iron supplements may
hasten joint deterioration
By Diana Swift
WWASHINGTON, D.C. - The iron supplements that many arthritic children
take to combat concomitant anemia may be hastening the deterioration of
their joints, Houston researchers say.
Led by biologist Roman Shypailo of the Children's Nutrition Research
Centre at Baylor College of Medicine, a Texas team looked at eight
children being treated for juvenile rheumatoid arthritis. The patients,
aged five to 15 years, received an intravenous radioactive tracer dose
of iron (0.03 microsievert). Iron activity in affected joints was
monitored on a position/energy-sensitive gamma counter, while a second
machine monitored whole-body iron retention. Iron deposition was
measured two hours post-infusion and again at days seven, 14, 28 and
56.
Anemic
"We found that iron excessively accumulates in arthritic joints and
probably contributes to the chronic damage," said Shypailo. "That puts
you between a rock and a hard place because many of these arthritic
kids are anemic and need iron supplements, which may worsen the
disease."
The study found a high level of agreement between the joint data and
the whole-body data, with a greater than 90% retention rate of the
infused iron both in joints and systemically. Furthermore, six of eight
patients showed increased uptake at the affected joints: 165% over the
first 30 days compared with initial uptake at two hours.
The next step, he says, is to see if there is excessive deposition of
dietary iron in arthritic joints.
Ann Rheum Dis 1989 May;48(5):382-8
Investigation of the anti-inflammatory properties of
hydroxypyridinones.
Hewitt SD, Hider RC, Sarpong P, Morris CJ, Blake DR
Cancer Research Unit, University of York, Heslington.
Synovial iron deposition associated with rheumatoid disease may
result
in the production of highly reactive oxygen free radicals, leading
to
tissue damage. This chain of events can be interrupted by iron
chelation. Families of strong iron (III) chelators have been tested
for their iron scavenging properties in vitro and their effects
assessed in vivo using a rat model of inflammation. All the
chelators
competed successfully for iron with apotransferrin, and some removed
up to 34% of iron from ferritin. The best anti-inflammatory effects
were achieved with the most hydrophilic chelators and those which
chelated iron most avidly. Activity was dependent on dose. The route
of administration was also an important factor with lower affinity
chelators. This work introduces a range of simple bidentate iron
chelators, which under certain conditions exceed desferrioxamine in
their iron scavenging abilities, and some of which, in this simple
animal model, approach indomethacin in their anti-inflammatory
capabilities.
Comments:
* Comment in: Ann Rheum Dis 1990 Nov;49(11):956-7
PMID: 2730166, UI: 89272259
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Tom
Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
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Re: Mother of young sufferer -- Posted by greenknees on 05-03-05 04:52
blank faced. | 
