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--- Cervical Spondylosis
"John" news:4289550e$0$39088$ed2e19e4@ptn-nntp-reader04.plus.net... > Does anyone have any useful in formation on this problem - treatments, > prognosis etcetera? > > John I do not know if this will help you or not but it was post here in the past. Harv CHAPTER 2 UNDERSTANDING ARTHRITIS Genetic markers of greatest interest to arthritis experts are the proteins known as human leukocyte antigens (HLA), which are located on the surfaces of most cells in the body. These markers were first discovered in the late 1960s. Scientists called them the human leukocyte antigens because they were first found on the surface of human leukocytes, another name for white blood cells. These antigens are involved in the immune system's ability to distinguish normal cells from foreign invaders. Scientists first studied the human leukocyte antigens because of the effect they had on organ transplants. A transplant was more likely to be susessful if the donor and recipient had similar or matching antigens. Some years later, certain genetic markers were found to be associated with certain kinds of disease. These diseases included four major kinds of rheumatic disease: ankylosing spondylitis, rheumatoid arthritis, some forms of juvenile arthritis, and Reiter's syndrome (a form of arthritis that may develop as a complication of certain infections). The first clue to a relationship between the human leukocyte antigens and rheumatic diseases came in 1973. Scientists found an overwhelming association of one HLA marker known as HLA-B27 with AS and Reiter's syndrome. This marker is found in only 8% of white people and 2% of black people, but in 95% of white people with AS and 50% of black people with AS. The HLA-B27 antigen is also found in a high proportion of symptom-free relatives of these people. Although the presence of this marker conveys a susceptibility to AS, fewer than one in five HLA- B27 carriers actually develops the disease. Ankylosing spondylitis affects about two in one thousand white men. It was previously thought to be very rare in women, but today doctors and scientists know that AS may occur in a mild form in a larger number of women. ------------------------------------------------------------------------ CHAPTER FIFTEEN ANKYLOSING SPONDYLITIS POSSIBLE CAUSES Although the cause of spondylitis is unknown, scientists have discovered a stong genetic, or family, link. Almost all Caucasian people with spondylitis have the genetic marker known as HLA-B27. Some- one who has this genetic marker will not necessarily develop AS, but people who do have it are more likely to develop the disease than those who do not. Many scientists believe that AS results from a combination of the HLA-B27 marker and a trigger of some sort, most likely some kind of infection. The trigger may set off a reaction by the immune system that becomes abnormal and leads to the damaging inflammation of AS. ------------------------------------------------------------------------ UNDERSTANDING ARTHRITIS WHAT IT IS HOW TO TREAT IT HOW TO COPE WITH IT THE ARTHRITIS FOUNDATION Charles Scribner's Sons Macmillan Publishing Company New York, NY 10022 > >
Wearing of the condyles of the neck vertebrae. Frequently occurs with aging. Can be alleviated by exercises. My wife got it when she was about 40 and was told she had the cervical vertebrae of a 70 year old. She has exercised successfully since and is now 65. See a rheumatologist for proper diagnosis and treatment. Peter Harvey R. Stone wrote: > "John" > news:4289550e$0$39088$ed2e19e4@ptn-nntp-reader04.plus.net... > > Does anyone have any useful in formation on this problem - treatments, > > prognosis etcetera? > > > > John > > > I do not know if this will help you or not but it was post here in the > past. > Harv > > > CHAPTER 2 > > UNDERSTANDING ARTHRITIS > > Genetic markers of greatest interest to arthritis experts are the > proteins known as human leukocyte antigens (HLA), which are located on > the surfaces of most cells in the body. These markers were first > discovered in the late 1960s. Scientists called them the human > leukocyte antigens because they were first found on the surface of > human leukocytes, another name for white blood cells. These antigens > are involved in the immune system's ability to distinguish normal cells > from foreign invaders. > Scientists first studied the human leukocyte antigens because of the > effect they had on organ transplants. A transplant was more likely to be > susessful if the donor and recipient had similar or matching antigens. > Some years later, certain genetic markers were found to be associated > with certain kinds of disease. These diseases included four major kinds > of rheumatic disease: ankylosing spondylitis, rheumatoid arthritis, some > forms of juvenile arthritis, and Reiter's syndrome (a form of arthritis > that may develop as a complication of certain infections). > The first clue to a relationship between the human leukocyte antigens > and rheumatic diseases came in 1973. Scientists found an overwhelming > association of one HLA marker known as HLA-B27 with AS and Reiter's > syndrome. This marker is found in only 8% of white people and 2% of > black people, but in 95% of white people with AS and 50% of black > people with AS. The HLA-B27 antigen is also found in a high proportion > of symptom-free relatives of these people. Although the presence of > this marker conveys a susceptibility to AS, fewer than one in five HLA- > B27 carriers actually develops the disease. > Ankylosing spondylitis affects about two in one thousand white men. > It was previously thought to be very rare in women, but today doctors > and scientists know that AS may occur in a mild form in a larger number > of women. > ------------------------------------------------------------------------ > > CHAPTER FIFTEEN > > ANKYLOSING SPONDYLITIS > > POSSIBLE CAUSES > > Although the cause of spondylitis is unknown, scientists have > discovered a stong genetic, or family, link. Almost all Caucasian > people with spondylitis have the genetic marker known as HLA-B27. Some- > one who has this genetic marker will not necessarily develop AS, but > people who do have it are more likely to develop the disease than those > who do not. > Many scientists believe that AS results from a combination of the > HLA-B27 marker and a trigger of some sort, most likely some kind of > infection. The trigger may set off a reaction by the immune system that > becomes abnormal and leads to the damaging inflammation of AS. > ------------------------------------------------------------------------ > > UNDERSTANDING ARTHRITIS > WHAT IT IS > HOW TO TREAT IT > HOW TO COPE WITH IT > > THE ARTHRITIS FOUNDATION > > Charles Scribner's Sons > Macmillan Publishing Company > New York, NY 10022 > > > > > > > Related Discussion: Wanna make some easy money? (1 posts) All about health-Discover healthful benefits of 100% natural products, herbal products and supplements. (4 posts) OneTouch Ultra Readings? (4 posts) Vegetarian Glucosamine Information Needed (1 posts) Top Discussions From Our Archives Total Diabetes Management System Software for PalmOS what should be the minimum time period between two consecutive nuclear bone scans? Lose Weight, Feel GREAT, Make Money!!! Other Discussion Categories Diabetes Symptoms Health Care Policy Health Care Providers HMO Arthritis Symptoms
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