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Iron induced increase in adjuvant arthritis synovitis


Iron induced increase in adjuvant arthritis synovitis -- Posted by ironjustice@aol.com on 07-17-05 14:21


So according to this study .. bread .. or ANYTHING .. fortified with
iron .. could .. be a .. problem .. ?

Ann Rheum Dis. 1992 Apr;51(4):516-21. Related Articles, Links


Effect of iron complexes on adjuvant arthritis in rats.

Dabbagh AJ, Blake DR, Morris CJ.

Inflammation Group, London Hospital Medical College, United Kingdom.

When a total dose infusion of iron dextran is given to anaemic
rheumatoid patients an exacerbation of inflammatory synovitis in
previously affected joints is observed. The adjuvant arthritis model of
inflammation in rats has been used to investigate the mechanism of iron
promoted synovitis. Either iron dextran (5 mg injected intravenously)
with a dextran C control, or iron sorbitol (7.5 mg injected
intramuscularly) with a sorbitol citrate complex control was given at
the onset of clinical joint inflammation. Iron dextran significantly
increased joint inflammation (assessed by joint scoring) at days 12,
13, 14, and 16 after injection. Similarly, iron sorbitol produced a
significant increase in the joint score at days 17, 18, 19, and 21. In
addition, extensive osteoporosis was observed in the rats treated with
iron sorbitol. These pro-inflammatory effects of iron coincide with the
presence of positive results for synovial iron (III) using Perl's test
and neutrophil infiltration. The results of this study suggest that the
iron induced increase in synovitis in adjuvant arthritis is a result of
iron promoted oxidative damage and is not likely to be due to the
dextran C or the sorbitol citric acid components. It is suggested that
a similar mechanism may occur in rheumatoid patients given iron
supplements.

PMID: 1586252 [PubMed - indexed for MEDLINE]

--------------------------------------------------------------------------------



Who loves ya.
Tom

Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking


Re: Iron induced increase in adjuvant arthritis synovitis -- Posted by d'huit on 07-17-05 16:00



wrote in message
news:1121635297.936897.209370@f14g2000cwb.googlegroups.com...
> So according to this study .. bread .. or ANYTHING .. fortified with
> iron .. could .. be a .. problem .. ?
>

boy rusty, if you adhere to the constraints your fears impose on you, your
diet must be a total bore. i just had a scathingly brilliant idea!

hey, rusty! sugar is not good for you. salt is not good for you. fats are
not good for you. carbs are not good for you. grains, fruits and veggies
have pesticides sprayed on them and are often grown in contaminated soils.
fish is polluted with mercury and other nasty things. chicken and red meats
have chemicals added to their feed. water is not safe to drink. you can
never tell what foods aren't contaminated, rusty. please, don't eat or
drink anything, rusty! it's too scary to eat or drink anything.

you are getting very sleepy, rusty. very sleepy. listen to the sound of my
voice---it's too scary to eat or drink anything. it's too scary to eat or
drink anything. it's too scary to eat or drink anything. it's too scary to
eat or drink anything.

kate
(thinking: if this works--we won't have to bother with rusty's goofy
obsession in the very near future! )





Re: Iron induced increase in adjuvant arthritis synovitis -- Posted by wc on 07-17-05 18:58


Kate,

Be assured and comforted that you are buried deep in the Nursing
Killfile. We just aren't interested in your arthritis or your iron.
Call us mean, call us unprofessional, but you, your iron, and your ilk
must quit your filthy crossposting, or enter the killfile, forever.


Will, CRNA


Re: Iron induced increase in adjuvant arthritis synovitis -- Posted by firechief on 07-17-05 23:15


"wc" wrote:

> Kate,
>
> Be assured and comforted that you are buried deep in the Nursing

> Killfile. We just aren't interested in your arthritis or your iron.
> Call us mean, call us unprofessional, but you, your iron, and your ilk
> must quit your filthy crossposting, or enter the killfile, forever.

It works both ways. GOOD-BYE forever.



Re: Iron induced increase in adjuvant arthritis synovitis -- Posted by spodosaurus on 07-18-05 04:42


wc wrote:
> Kate,
>
> Be assured and comforted that you are buried deep in the Nursing
> Killfile. We just aren't interested in your arthritis or your iron.
> Call us mean, call us unprofessional, but you, your iron, and your ilk
> must quit your filthy crossposting, or enter the killfile, forever.
>
>
> Will, CRNA

Will, when a troll crossposts deliberately, not all respondants will
notice the mass crossposting when they reply. Just like YOU didn't
notice the crossposting or apparently comprehend that Kate was replying
to a nasty little cultist (he's still hoping to find another person to
join his cult) troll. So, you either have serious reading comprehension
problems (potentially a very serious problem in your profession) or
you're a hypocrite, or both.

Cheers,

Ari

--
spammage trappage: replace fishies_ with yahoo

I'm going to die rather sooner than I'd like. I tried to protect my
neighbours from crime, and became the victim of it. Complications in
hospital following this resulted in a serious illness. I now need a bone
marrow transplant. Many people around the world are waiting for a marrow
transplant, too. Please volunteer to be a marrow donor:
http://www.abmdr.org.au/
http://www.marrow.org/


Re: Iron induced increase in adjuvant arthritis synovitis -- Posted by ironjustice@aol.com on 07-18-05 17:06


Got something to say about iron OR .. arthritis .. ?

Then S-T-F-U ..

Who loves ya.
Tom
Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com
Man Is A Herbivore!
http://pages.ivillage.com/ironjustice/manisaherbivore
DEAD PEOPLE WALKING
http://pages.ivillage.com/ironjustice/deadpeoplewalking

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