 |  |
 |  |  | |||||||
|
--- Painkillers linked to hypertension
Sorry, Brian, I should have noticed your post but didn't. Thanks for posting. PeterB Roman Bystrianyk wrote: > DELTHIA RICKS, "Painkillers linked to hypertension", Newsday, August > 17, 2005, > Link: > http://www.newsday.com/news/health/ny-hspain17,0,2776521.story?coll=ny-top-headlines > > Women who rely on the popular painkillers acetaminophen and ibuprofen > are more likely to develop high blood pressure than those who don't > take the over-the-counter drugs, a team of doctors said yesterday. > > Daily use of either medication can increase the risk of hypertension by > more than 90 percent, say medical researchers at Brigham and Women's > Hospital in Boston, who questioned 5,123 participants in the Nurses' > Health Study. > > Acetaminophen, widely sold in a variety of strengths, is best known by > such brand names as Tylenol, Panadol and Liquiprin. Ibuprofen is sold > as Advil and Motrin, among a host of other brands. Both acetaminophen > and ibuprofen are analgesics that numb pain. But ibuprofen can be > narrowed further into the class called nonsteroidal anti-inflammatory > drugs, or NSAIDs, of which aspirin is a member. Aspirin has not been > found to have an adverse effect on blood pressure. > > "Given the widespread use of painkillers, especially among women, it is > critical to understand the potential side effects associated with > frequent, high-dose consumption," said Dr. John Forman, a hypertension > specialist in the hospital's division of renal medicine. > > Forman and his team examined the use of painkillers in two groups of > women: one made up of those between the ages of 51 and 77; the other > composed of those between ages of 34 and 53. The groups were further > divided among those who used painkillers and those who did not. > > Older women who reported taking the highest doses of acetaminophen, 500 > milligrams a day, had a 93 percent increased risk of hypertension > compared with women who refrained. Among younger women who regularly > took the medication, the hypertension risk was double that of nonusers. > Older women who routinely took ibuprofen, at a high dose of 400 > milligrams daily, had a risk of hypertension of 78 percent; for younger > women, risk was elevated by 60 percent. > > Evidence against common painkillers -- prescription-grade as well as > over-the-counter -- has been mounting for nearly a year. In September, > Vioxx, a prescription NSAID, was withdrawn from the market after > researchers found it escalated the risk of heart attack and stroke. > > In June, Dr. Julia Hippisley-Cox of the University of Nottingham in > Britain raised questions about the safety of ibuprofen. She found a > 24-percent increased risk of heart attack in people of either gender > who used the painkiller daily. > > Dr. David L. Brown, chief of cardiovascular medicine at Stony Brook > University Hospital, said it is not well known how either acetaminophen > or ibuprofen raises blood pressure. "One hypothesis is that people who > take very high doses of acetaminophen and nonsteroidal > anti-inflammatories experience kidney damage." > > The kidneys play a critical role in the maintenance of healthy blood > pressure. But Brown said the Boston research does not provide enough > information. "The study is observational," he said. "And I think these > kinds of studies have to be interpreted with a lot of caution." > Nevertheless, Brown added that consumers can't assume that because a > drug is sold over the counter it carries no risks.
And how might Paracetemol compare in this field of view? "Roman Bystrianyk" news:1124271732.304509.87640@g43g2000cwa.googlegroups.com... > DELTHIA RICKS, "Painkillers linked to hypertension", Newsday, August > 17, 2005, > Link: > http://www.newsday.com/news/health/ny-hspain17,0,2776521.story?coll=ny-top-headlines > > Women who rely on the popular painkillers acetaminophen and ibuprofen > are more likely to develop high blood pressure than those who don't > take the over-the-counter drugs, a team of doctors said yesterday. > > Daily use of either medication can increase the risk of hypertension by > more than 90 percent, say medical researchers at Brigham and Women's > Hospital in Boston, who questioned 5,123 participants in the Nurses' > Health Study. > > Acetaminophen, widely sold in a variety of strengths, is best known by > such brand names as Tylenol, Panadol and Liquiprin. Ibuprofen is sold > as Advil and Motrin, among a host of other brands. Both acetaminophen > and ibuprofen are analgesics that numb pain. But ibuprofen can be > narrowed further into the class called nonsteroidal anti-inflammatory > drugs, or NSAIDs, of which aspirin is a member. Aspirin has not been > found to have an adverse effect on blood pressure. > > "Given the widespread use of painkillers, especially among women, it is > critical to understand the potential side effects associated with > frequent, high-dose consumption," said Dr. John Forman, a hypertension > specialist in the hospital's division of renal medicine. > > Forman and his team examined the use of painkillers in two groups of > women: one made up of those between the ages of 51 and 77; the other > composed of those between ages of 34 and 53. The groups were further > divided among those who used painkillers and those who did not. > > Older women who reported taking the highest doses of acetaminophen, 500 > milligrams a day, had a 93 percent increased risk of hypertension > compared with women who refrained. Among younger women who regularly > took the medication, the hypertension risk was double that of nonusers. > Older women who routinely took ibuprofen, at a high dose of 400 > milligrams daily, had a risk of hypertension of 78 percent; for younger > women, risk was elevated by 60 percent. > > Evidence against common painkillers -- prescription-grade as well as > over-the-counter -- has been mounting for nearly a year. In September, > Vioxx, a prescription NSAID, was withdrawn from the market after > researchers found it escalated the risk of heart attack and stroke. > > In June, Dr. Julia Hippisley-Cox of the University of Nottingham in > Britain raised questions about the safety of ibuprofen. She found a > 24-percent increased risk of heart attack in people of either gender > who used the painkiller daily. > > Dr. David L. Brown, chief of cardiovascular medicine at Stony Brook > University Hospital, said it is not well known how either acetaminophen > or ibuprofen raises blood pressure. "One hypothesis is that people who > take very high doses of acetaminophen and nonsteroidal > anti-inflammatories experience kidney damage." > > The kidneys play a critical role in the maintenance of healthy blood > pressure. But Brown said the Boston research does not provide enough > information. "The study is observational," he said. "And I think these > kinds of studies have to be interpreted with a lot of caution." > Nevertheless, Brown added that consumers can't assume that because a > drug is sold over the counter it carries no risks. > Related Discussion: FREE PHONSEX DATING - these girls are not paid - they call for phonesex with guys 6392 (1 posts) First Vioxx, now Bextra? (3 posts) Insurance rates (3 posts) nutritional products (1 posts) Top Discussions From Our Archives Most Effective Herbal Treatment For Acne Control Water: How much should you drink every day? Other Discussion Categories Diabetes Symptoms Health Care Policy Health Care Providers HMO Arthritis Symptoms Oops!!! Unexpected Error While Reading the Feed
|
| ||||||||
 |  |
