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Elimination of arthritis pain and inflammation / anti-iron
Elimination of arthritis pain and inflammation / anti-iron -- Posted by ironjustice@aol.com on 08-27-05 09:02
<>
may be effective in terminating pain and inflammation of arthritis for
years, often with a single treatment
<>
Med Hypotheses. 2005 Aug 22; [Epub ahead of print] Related Articles,
Links
Elimination of arthritis pain and inflammation for over 2years with a
single 90min, topical 14% gallium nitrate treatment: Case reports and
review of actions of gallium III.
Eby G.
George Eby Research, 14909-C Fitzhugh Road, Austin, TX 78736, United
States.
Arthritis is inflammation in a joint often with joint damage, usually
accompanied by pain, swelling and stiffness, resulting from infection,
trauma, degenerative changes, metabolic disturbances, autoimmune or
other causes. It occurs in various forms, including rheumatoid
arthritis, osteoarthritis, bacterial arthritis and gout. Gallium III
can inhibit the production of inflammatory cytokines, such as IL-1beta,
produced by macrophage-like cells in vitro. A dose-dependent inhibition
of IL-1beta and TPA stimulated MMP activity by gallium nitrate at
increasing concentrations occurs, demonstrating that gallium nitrate
can be a useful modulator of inflammation in arthritis. Gallium III is
an inhibitor of bone resorption and is an effective treatment for
hypercalcemia. Gallium III has been reported to be effective in the
treatment of mycobacterium butycicum-induced arthritis in rats by
antagonism of iron III. Long-term elimination of pain from arthritis by
gallium III was first observed in horses primarily being treated for
navicular disease. Several people treating their horses with gallium
nitrate coincidentally found that arthritis pain in their fingers ended
and did not return after soaking their hands in 14% gallium nitrate
solution. Therefore, the severely arthritic hands of a 60-year-old
woman were topically treated with a 14% aqueous solution of gallium
nitrate for 90min. Pain and inflammation from rheumatoid arthritis
diminished rapidly, and neither pain nor inflammation returned during
the following 2years from that single treatment. A 61-year-old woman
who had osteoarthritis in her left knee, shoulders and wrists was
treated orally with 50ml of a 1% gallium nitrate solution (120mg
elemental gallium) daily using a two week on and two week off protocol,
resulting in almost total elimination of pain while on gallium nitrate,
while pain partially returned during the two week off periods.
Treatment of frozen shoulder with topical 40% gallium nitrate for
120min resulted in greatly reduced pain and crepitus almost immediately
with complete restoration of range of motion, with pain remaining
essentially absent for over 1year. Mechanisms of action are
hypothesized to include anti-inflammatory, bone density improvements,
antibacterial, anti-iron III and anti-aluminum III effects. Proper use
of gallium III may be effective in terminating pain and inflammation of
arthritis for years, often with a single treatment.
PMID: 16122880 [PubMed - as supplied by publisher]
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