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Relations Among Heart Disease, Diabetes and Dementia Investigated
Relations Among Heart Disease, Diabetes and Dementia Investigated -- Posted by Gumbo on 11-02-04 04:56
Relations Among Heart Disease, Diabetes and Dementia Investigated
Researchers examine the relations among atherosclerosis, heart disease, type
2 diabetes, and dementia in a recent issue of Neurological Research.
"Type 2 diabetes in the elderly is associated with increased incidence of
vascular disease, particularly, atherosclerosis of large blood vessels.
Together with other risk factors such as dyslipidemia, atherosclerosis
increases the risk for coronary heart disease and stroke, Most studies that
have examined the impact of type 2 diabetes and other heart disease risk
factors on cognitive functions do not provide evidence that heart disease
risk factors (with the possible exception of triglycerides) further increase
the likelihood of observing cognitive deficits in diabetic patients,"
scientists in Canada report.
"However, none of these studies used imaging techniques to evaluate
atherosclerosis or evidence of cerebrovascular disease, such as
infarctions," said Claude Messier and colleagues at the University of
Ottawa. "The few studies that have included brain imaging suggest that
evidence of cerebrovascular disease further increases the risk for dementia
in diabetic patients. The results of longitudinal studies suggest that
diabetes is an independent risk factor for cognitive decline and dementia.
The pattern of neuro psychological performance observed in type 2 diabetic
patients appears to be the result of multiple interacting processes
developing over time."
"In addition to the detrimental effects of protracted impaired glucose
regulation on the central nervous system, type 2 diabetes pathology also
encompasses the detrimental effects of associated complications such as
cerebrovascular disease, which is likely the main cause of the observed
processing speed/reaction time decrements," concluded the investigators.
Messier and his coauthors published their study in Neurological Research
(The relationships between atherosclerosis, heart disease, type 2 diabetes
and dementia. Neurol Res, 2004;26(5):567-572).
For more information, contact Michele Gagnon, School of Psychology,
University of Ottawa, 145 Jean Jacques Lussier, Room 352, Ottawa, ON K1N
6N5, Canada.
Publisher contact information for the journal Neurological Research is:
Maney Publishing, Hudson Road, Leeds LS9 7DL, England.
The information in this article comes under the major subject areas of
Diabetes Complications, Type 2 Diabetes, Diabetes Survival and Mortality,
Dementia, Cognition, Endocrinology, Heart Disease Risk Factor, Neuroscience,
and Atherosclerosis Risk Factor.
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