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Grafts help heal diabetic foot ulcers


Grafts help heal diabetic foot ulcers -- Posted by Gumbo on 11-09-04 17:55


Grafts help heal diabetic foot ulcers
Oct 24 (Reuters Health) - Diabetic patients are prone to develop sores on
their feet that are notoriously difficult to treat. Now, new research has
shown that grafts derived from a patient's skin cells can help some diabetic
ulcers heal faster, new research shows.


These findings come from a study, published in the current issue of Diabetes
Care, that compared such grafts with standard gauze dressings in 79
diabetics with ulcers on the top or bottom of their feet.


The grafts were created by taking skin samples from each patient and then
growing the skin cells in a lab to form a sheet that could be used to cover
the patient's ulcer.


All of the patients had their ulcers cleaned thoroughly, received
antibiotics if needed, and were given casts to relieve pressure if the ulcer
was on the bottom of the foot, lead author Dr. Carlo Caravaggi, from the
Ospedale di Abbiategrasso in Milan, and colleagues note.


Grafting was safe and well tolerated, the authors report. Among patients
with ulcers on the top of the foot, 67 percent of grafted ulcers healed
compared with just 31 percent of gauze-treated ulcers. Among patients with
ulcers on the bottom of the foot, however, about 52 percent of ulcers healed
regardless of treatment type.


Although grafting appears to be more effective for top-of-foot ulcers, the
authors note that it may still be of use for bottom-foot ulcers, especially
when the optimal pressure-relieving cast cannot be used.


SOURCE: Diabetes Care, October 2003.




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