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Skin test provides insight into heart disease risk
Skin test provides insight into heart disease risk -- Posted by Gumbo on 11-16-04 04:59
Skin test provides insight into heart disease risk
Oct 29 (HeartCenterOnline) - A new test that measures the level of sterol in
the skin may help doctors identify people at risk for developing coronary
artery disease (CAD).
The test, called the PREVU Point of Care Sterol Test, is a non-invasive way
to measure skin tissue cholesterol in some patients. Cholesterol is a major
risk factor for cardiovascular disease.
In a study presented at the annual Canadian Cardiovascular Congress, on
October 25, physicians gave the results from 300 patients with proven
coronary artery disease, 90 percent of whom were on statin medications. They
found that skin sterol levels were elevated in high-risk patients, and there
was a positive correlation between skin sterol levels and chest pain and
diabetes.
These findings so far seem limited to patients with established CAD who are
taking cholesterol-lowering medications. Previous studies have shown there
is no correlation between skin sterol levels and blood cholesterol levels in
patients who are not taking cholesterol-lowering medications.
However, there is an established link between skin sterol levels and history
of heart attacks, as well a relationship between skin sterol and various
cardiovascular risk factors.
For patients with a previous history of heart disease, including CAD, and
who are on statin medications, the new test might provide physicians with a
non-invasive tool to classify them based on risk levels.
"Our findings confirm previous clinical evidence that skin sterol provides
new information about heart disease risk independent of blood cholesterol
and other traditional risk factors," said Dr. Milan Gupta, assistant
clinical professor, Department of Medicine, McMaster University, in
Hamilton, Ontario, and investigator in the clinical trial.
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