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Incidence of Diabetes After Kidney Transplant Increasing


Incidence of Diabetes After Kidney Transplant Increasing -- Posted by Gumbo on 11-26-04 08:14


Incidence of Diabetes After Kidney Transplant Increasing


Originally Published:20041101.

An increasing number of people appear to be developing diabetes for the
first time after kidney transplant, increasing their risk of transplant
complications and death, according to a Sept 2, 2004, news release from the
National Kidney Foundation. Moreover, people with pre-existing diabetes
appear to benefit more from kidney transplantation when it is performed
before they develop kidney failure, suggesting that physicians should
provide the option of transplantation to patients with diabetes sooner
rather than later.

As part of a recent study, more than 60 experts, including physicians,
surgeons, nurses, and allied health professionals, met to discuss
state-of-the-art approaches to treating patients who have diabetes and
advanced chronic kidney disease. The experts addressed the best techniques
for treating patients with diabetes before transplant, managing kidney
disease in patients with diabetes, treating diabetes after transplantation,
and improving long-term kidney transplant outcomes in patients with
diabetes.

The work groups found that an increasing number of people appear to be
developing diabetes for the first time after kidney transplant. As a result,
they suffer as many adverse ill effects during an eight-to-10-year period as
people who had preexisting diabetes, largely because of their increased risk
of cardiovascular disease. Experts noted that some people diagnosed with
post transplant diabetes mellitus likely had undetected signs of the
condition before the transplant.

The same factors that put people at risk for diabetes before transplant
likely increased the risk of diabetes after transplant, the experts noted.
These risk factors include a family history of the disease, increased age,
and obesity. Additionally, some of the medications that help prevent the
body from rejecting the new organ have been linked to an increased risk of
post transplant diabetes mellitus.

To prevent diabetes and manage pre-existing diabetes in kidney transplant
patients, the experts recommend that physicians try to modify transplant
medications without increasing the risk of rejection and encourage patients
to adopt the same techniques that help prevent and manage diabetes in the
general population, including losing weight, exercising, and taking
medications to reduce blood pressure and cholesterol.

Diabetes After Kidney Transplant on the Rise (news release, New York:
National Kidney Foundation, Sept 2, 2004)




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