---
Computer Modeling to Aid Fight Against Diabetes
Computer Modeling to Aid Fight Against Diabetes -- Posted by Gumbo on 11-26-04 08:17
Computer Modeling to Aid Fight Against Diabetes
A biotechnology company specializing in computer modeling of biologic
systems has announced its intention to develop a model of the non-obese
diabetic (NOD) mouse, the animal model most often used to study type 1
diabetes.
Although researchers use many types of animals to study diseases and drug
responses, often results obtained from animals differ from those found for
human subjects. The NOD model to be developed by Entelos (Foster City, CA,
USA) is designed to bridge this gap by translating results from pre-clinical
animal studies into predictions for the outcome of human trials.
The model will be built in collaboration with the American Diabetes
Association (ADA) and a scientific advisory board they select to guide and
oversee the development of the NOD PhysioLab platform.
Dr. Mikhail Gishizky, Entelos CSO, said, Translational medicine--translating
observations made in pre-clinical animal model systems to human in vivo
responses--is a complex issue posing significant challenges to the
development of therapeutics for treating human disease. Although numerous
therapies have been shown to inhibit the development of type 1 diabetes in
the NOD mouse, success in advancing these therapies to human patients has
been limited. Through the use of predictive mathematical models, the
research community will have a significant scientific advancement which will
ultimately improve the rationale for taking novel interventions into humans.
To see more of Medinews.com, or to subscribe, go to http://www.medinews.com
Related
Discussion:
Studies with RF Negative Participants (1 posts)
by Andy Katz - Last post on: 01-24-05 20:44
Hello everyone,
My wife suffers sero-negative PA which has been refractory to most
dmards and tnf inhibitors. We're in the NY area and she's willing to
participate in a study--stem cells in particular, but any other
promising therapy--but the criteria for most seem to include being
sero-posit... (Read More)
help with gout question (8 posts)
by mig - Last post on: 01-27-05 10:43
Help! My husband will not go to a doctor. He believes that hospitals
and doctors are for sick people. ;-/
He gets pains in his toes. The pain, or burning feeling, usually starts
at night. He also gets the sweats.
While he has the "attack", it hurt to walk because of the pain in his
toes.
... (Read More)
Re: New to Diabetes--please help (2 posts)
by tim kettring - Last post on: 08-14-03 08:49
She Absolutely MUST have a Blood-Glucose-Meter!!! , I got mine and 50
test-strips for about $30 . E-mail if you need details . She needs to
test AT LEAST 3 times a day !!! And Especially if she feels Like that
!!!
More experienced people will reply Pronto .
tim
Lisa wrote in message ... (Read More)
The fountain of youth (2 posts)
by Tim Jundt - Last post on: 05-11-05 17:26
Go to my web site and feel younger, look younger, lose all of your aches and
pains and, if you want, make a ton of money! Any questions, please contact
me through my site. Thank you for looking.
http://www.myviaoffice.com/jundtman
... (Read More)
Top
Discussions From Our Archives
Germ Study Suggests Bloodletting May Work
[Fwd: MILLIONAIRE showers with LADYbug!]
Scientific Breakthrough
AmeriPlanUsa
Zyprexa and diabetes
Other
Discussion Categories
Diabetes Symptoms
| 
