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Fad Diets High in Saturated Fats Can Induce Insulin Resistance
Fad Diets High in Saturated Fats Can Induce Insulin Resistance -- Posted by Gumbo on 12-05-04 06:59
Fad Diets High in Saturated Fats Can Induce Insulin Resistance
Fad diets high in saturated fats can induce insulin resistance.
According to scientists in the United States, "Insulin resistance is a
central pathogenic factor for the metabolic syndrome and is associated with
both generalized obesity and the accumulation of fat in the omental and
intramyocellular compartments.
"In the context of the current obesity epidemic, it is imperative to
consider diets in terms of their ability to both promote weight loss and
ameliorate insulin resistance."
"Weight loss under any dietary formulation depends on hypocaloric intake,
and only moderate weight loss (5-10%) is sufficient to augment insulin
sensitivity. However," said C. Laracastro and coworkers, " increments in
insulin sensitivity may be more directly related to loss of intramyocellular
or omental fat rather than loss of total body weight per se."
"The widespread acceptance of popular low-carbohydrate high-fat diets (e.g.
Atkins Diet, Zone Diet, South Beach diet) further underscores the need to
evaluate dietary interventions regarding their safety and metabolic effects.
These high-fat diets have been shown to be safe in the short term; however,"
the authors continued, "their long-term safety has not been established."
"With respect to insulin sensitivity, diets enriched in saturated fats can
induce insulin resistance, whereas fat substitution with monounsaturated
fats can enhance insulin sensitivity. On the other hand, high-fiber,
high-carbohydrate diets comprised of foods with low caloric density can
similarly be used for effective weight reduction and to ameliorate insulin
resistance.
"Although some data suggest that low-glycemic index diets are most
advantageous in this regard," wrote scientists, "these effects may have more
to do with increments in dietary fiber than differences in available
carbohydrates."
The authors concluded, "Popular low-carbohydrate, high-fat diets are being
fervently embraced as an alternative to challenging modifications in
lifestyle and intentional calorie reduction."
"Current data do not support such unbridled enthusiasm for these diets,
particularly in relationship to high-fiber, high-carbohydrate diets
emphasizing intake of fresh vegetables and fruits. Long-term studies to
determine the efficacy and safety of both popular and experimental diets are
warranted."
Laracastro and colleagues published their study in the Journal of Clinical
Endocrinology and Metabolism (Diet, insulin resistance, and obesity: Zoning
in on data for Atkins dieters living in South Beach. J Clin Endocrinol
Metab, 2004;89(9):4197-4205).
For additional information, contact W.T. Garvey, University Alabama,
Department Nutrition Science, Webb 232, 1675 University Blvd., Birmingham,
AL 35294, USA.
The publisher's contact information for the Journal of Clinical
Endocrinology and Metabolism is: Endocrine Society, 8401 Connecticut Avenue,
Suite 900, Chevy Chase, MD 20815-5817, USA.
The information in this article comes under the major subject areas of
Diabetes, Insulin Resistance, Diet and Nutrition, Saturated Fat, and Fad
Diets. This article was prepared by Biotech Law Weekly editors from staff
and other reports. Copyright 2004, Biotech Law Weekly via LawRx.com.
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