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Actos diabetes drug bests Avandia in lipid study
Actos diabetes drug bests Avandia in lipid study -- Posted by Gumbo on 12-05-04 21:55
Actos diabetes drug bests Avandia in lipid study
Nov 11 (Reuters) - A Takeda Pharmaceuticals diabetes drug was more effective
in dealing with patients' cholesterol problems than a rival made by
GlaxoSmithKline in a head-to- head study reported on Wednesday.
The 735-person, 24-week study presented at the American Heart Association
scientific meeting, tested Takeda's Actos against Glaxo's Avandia in
diabetics in whom high levels of triglycerides and low levels of HDL, the
so- called good cholesterol, are common problems.
While both drugs were equally effective in their primary job of improving
blood sugar levels, researchers found that Actos was significantly better at
lowering triglycerides and raising HDL levels than Avandia.
Triglycerides are considered to be a risk factor for heart disease, while a
body of evidence is building that higher HDL levels may help reduce heart
risk.
Takeda has been selling Actos, or pioglitazone, in the United States since
1999 in partnership with Eli Lilly and Co. It had global sales of $1.68
billion in its last full fiscal year.
Glaxo reported combined 2003 sales of $1.66 billion for Avandia, also known
as rosiglitazone, and Avandamet, which combines Avandia with another
diabetes drug metformin.
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