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Vitamin E helps diabetics fight heart disease
Vitamin E helps diabetics fight heart disease -- Posted by Gumbo on 12-17-04 19:06
Vitamin E helps diabetics fight heart disease
(HeartCenterOnline) - After two weeks of difficult news, vitamin E finally
got some good press when a study revealed that the powerful antioxidant may
help some diabetics avoid heart disease.
A study showed that 40 percent of diabetics might benefit from taking 400 IU
of vitamin E daily. Among this group, vitamin E reduced the risk of heart
attack and dying from heart disease. The findings were published in the
November issue of Diabetes Care.
These results were released only two weeks after a team of Johns Hopkins
researchers found that the risk of dying increased among people who take
400IU of vitamin E daily. The Johns Hopkins researchers reached this
conclusion by conducting a meta-analysis of existing studies on vitamin E.
The new study, conducted by researchers at the Technion- Israel Institute of
Technology in Haifa, Israel, identified a group of diabetics who have
abnormally low levels of antioxidants, along with abnormally high levels of
dangerous oxygen free radicals.
Free radicals are unstable molecules that are linked to a number of health
disorders through their ability to degrade healthy cells. Antioxidants
neutralize free radicals.
The Technion-Israel Institute researchers identified a group of diabetics
who had a particular type of blood protein called 2-2 haptoglobin. The 2-2
haptoglobin diabetics had a 500 percent increased risk of developing heart
disease. About 40 percent of diabetics have 2-2 haptoglobin.
When these patients took 400 IU of vitamin E daily, they reduced their risk
of heart attack by 43 percent and decreased their risk of dying of heart
disease by 55 percent.
These results were found by analyzing data gathered as part of the Heart
Outcomes Prevention Evaluation (HOPE) trial in 2000, which was designed to
study the effect of vitamin E therapy on heart disease. The HOPE trial found
there was no benefit from vitamin E on cardiovascular risk. However, it did
not separate patients based on their haptoglobin type.
Armed with these initial results, Dr. Andrew Levy, the author of the study
and a professor on the faculty of medicine at Technion-Israel, is launching
a large-scale, five-year study of 2,00 diabetics with 2-2 haptoglobin.
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