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CRP Levels Predict Type 1 Diabetes


CRP Levels Predict Type 1 Diabetes -- Posted by Gumbo on 12-24-04 06:10


CRP Levels Predict Type 1 Diabetes

Patients with diabetes suffered significantly greater dyslipidemia and
activated hemostasis and inflammation than those without diabetes.


Elevated C-reactive protein (CRP) is a marker of inflammation. Elevated CRP
has also been observed in people with type 2 diabetes, gestational diabetes,
and the metabolic syndrome.

Researchers, curious whether elevated CRP levels might also predict the
development of type 1 diabetes in children, performed a sub analysis of
children enrolled in the Diabetes Autoimmunity Study of the Young (DAISY),
and found that it just might. They suggest that future studies in diabetes
prevention consider the use of anti-inflammatory agents.

In a study of 4,066 British men aged 60-79 years, researchers identified 467
men with prevalent diabetes and 842 with prevalent coronary heart disease.

Concentrating on unconventional risk factors, researchers found that
patients with diabetes suffered significantly greater dyslipidaemia and
activated haemostasis and inflammation than those without diabetes. This
finding was even more apparent in those with no history of coronary heart
disease.

It remains to be seen whether reducing insulin resistance by
non-pharmacological or pharmacological therapy reduces activation of
haemostasis and inflammation.

Diabetes,53 (2569-2573): Elevated C-reactive protein levels in the
development of type 1 diabetes

Diabetologia,47 (1557-1565 Insulin resistance, haemostatic and inflammatory
markers and coronary heart disease risk factors in Type 2 diabetic men with
and without coronary heart disease





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