| | |
---
Vitamin E Linked to Increased Risk of Heart Failure
Vitamin E Linked to Increased Risk of Heart Failure -- Posted by Gumbo on 03-25-05 04:40
Vitamin E Linked to Increased Risk of Heart Failure
NEW YORK (Reuters Health) - The results of a seven-year study examining the
potential benefit of vitamin E in preventing cancer and cardiovascular
events in older patients with vascular disease or diabetes not only showed
no benefit from taking the supplement, it showed an increased risk of heart
failure, according to a report in the Journal of the American Medical
Association.
The original HOPE (Heart Outcomes Prevention Evaluation) trial found no
evidence that vitamin E affects the outcome of heart disease after 4.5
years. The study included approximately 9,500 patients, 55 years of age or
older, with vascular disease or diabetes assigned to a placebo or 400 IU per
day of vitamin E.
Thinking that the treatment period may have been too short to show a
benefit, Dr. Eva Lonn, at McMaster University in Hamilton, Ontario, and
colleagues, extended the HOPE study for 2.5 more years. In HOPE- The Ongoing
Outcomes (HOPE-TOO) trial, nearly 4,000 subjects continued in the trial.
There were no significant differences between the vitamin E group and the
placebo group in cancer rate, cancer deaths, major cardiovascular events
(heart attack, stroke, or death from cardiovascular causes), or death from
any cause in the extension study.
However, the risk of heart failure was higher in the vitamin E group than in
the placebo group (14.7 percent versus 12.6 percent), as was the risk of
hospitalization for heart failure (5.8 percent versus 4.2 percent).
"In conjunction with its lack of efficacy, the potential for harm suggested
by our findings strongly supports the view that vitamin E supplements should
not be used in patients with vascular disease or diabetes mellitus," Lonn's
group advises.
"HOPE-TOO reemphasizes the importance of controlled clinical trials for
testing important hypotheses deriving from basic biological findings or from
epidemiological observations," Dr. B. Greg Brown and Dr. John Crowley, at
the University of Washington in Seattle, write in an accompanying editorial.
SOURCE: Journal of the American Medical Association, March 16, 2005.
Re: Vitamin E Linked to Increased Risk of Heart Failure -- Posted by Tee on 03-26-05 15:01
I wonder if that would also include OMega 3 fish oil and flaxseed oil.
"Gumbo" wrote in message news:d210sf$j2h$0@pita.alt.net...
> Vitamin E Linked to Increased Risk of Heart Failure
>
> NEW YORK (Reuters Health) - The results of a seven-year study examining
the
> potential benefit of vitamin E in preventing cancer and cardiovascular
> events in older patients with vascular disease or diabetes not only showed
> no benefit from taking the supplement, it showed an increased risk of
heart
> failure, according to a report in the Journal of the American Medical
> Association.
>
> The original HOPE (Heart Outcomes Prevention Evaluation) trial found no
> evidence that vitamin E affects the outcome of heart disease after 4.5
> years. The study included approximately 9,500 patients, 55 years of age or
> older, with vascular disease or diabetes assigned to a placebo or 400 IU
per
> day of vitamin E.
>
> Thinking that the treatment period may have been too short to show a
> benefit, Dr. Eva Lonn, at McMaster University in Hamilton, Ontario, and
> colleagues, extended the HOPE study for 2.5 more years. In HOPE- The
Ongoing
> Outcomes (HOPE-TOO) trial, nearly 4,000 subjects continued in the trial.
>
> There were no significant differences between the vitamin E group and the
> placebo group in cancer rate, cancer deaths, major cardiovascular events
> (heart attack, stroke, or death from cardiovascular causes), or death from
> any cause in the extension study.
>
> However, the risk of heart failure was higher in the vitamin E group than
in
> the placebo group (14.7 percent versus 12.6 percent), as was the risk of
> hospitalization for heart failure (5.8 percent versus 4.2 percent).
>
> "In conjunction with its lack of efficacy, the potential for harm
suggested
> by our findings strongly supports the view that vitamin E supplements
should
> not be used in patients with vascular disease or diabetes mellitus,"
Lonn's
> group advises.
>
> "HOPE-TOO reemphasizes the importance of controlled clinical trials for
> testing important hypotheses deriving from basic biological findings or
from
> epidemiological observations," Dr. B. Greg Brown and Dr. John Crowley, at
> the University of Washington in Seattle, write in an accompanying
editorial.
>
> SOURCE: Journal of the American Medical Association, March 16, 2005.
>
>
Related
Discussion:
Diabetes Patients: See why it's called "The Greatest Vitamin in the World" (3 posts)
by jas3777 - Last post on: 12-14-03 07:15
You will never want to take a synthetic vitamin again.
"The Greatest Vitamin in the World" nutritionally supports people with
weight loss issues, stress, digestion/indigestion problems, blood
sugar level/diabetes, among a host of others. "The Greatest Vitamin
in the World" is endorsed by the... (Read More)
Celebex, Vioxx, Bextra, R.I.P. (3 posts)
by awthrawthr@yahoo.com - Last post on: 12-18-04 18:52
Now would be a good time to give natural alternatives a good trial.
There are many to choose from. There's the combo of MSM, chondroitin
sulfate & glucosamine sulphate.
There are numerous topical products. Try one with emu oil combined with
other pain releiving ingredients.
Fish oil with ... (Read More)
The Science on Chromium Supplements (1 posts)
by Gumbo - Last post on: 10-23-04 05:54
The Science on Chromium Supplements
The Hustle According to marketers, chromium supplements can help you lose
weight, boost metabolism, pack on muscle and fight heart disease. Some
preliminary research suggests that chromium can help regulate blood sugar
and improve insulin sensitivity, to t... (Read More)
Should You Count Those "Net Carbs" or "Low Impact" Carbs (1 posts)
by Gumbo - Last post on: 12-17-04 19:17
Should You Count Those "Net Carbs" or "Low Impact" Carbs
Every drugstore, supermarket, and department store in U.S. is filled with
snack products that claim to be perfect for low carb diet. The labels on
these products may list 24 grams of carbs but assure you that you only have
to count 2 ... (Read More)
Top
Discussions From Our Archives
Are you really Diabetic?
Re: New to Diabetes--please help
Teenage Boys Shat on By Fathers
sweetener experience and question
Important Breakthrough in Wellness Industry!
Certo for arthritis
Other
Discussion Categories
Diabetes Symptoms
Health Care Policy
Health Care Providers HMO
Arthritis Symptoms
Oops!!! Unexpected Error While Reading the Feed
|
|
