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Coffee, tea and diabetes: the role of weight loss and caffeine.
Coffee, tea and diabetes: the role of weight loss and caffeine. -- Posted by Sweet Zombie Jesus! on 06-01-05 08:23
OBJECTIVE:To assess the effect of weight change on the relationship
between coffee and tea consumption and diabetes risk.
DESIGN:Prospective cohort study, using data from the First National
Health and Nutrition Examination Survey Epidemiologic Follow Up Study.
Survival analyses were conducted using 301 selfreported cases of
diabetes and eight documented diabetes deaths during an 8.4-y
follow-up.SUBJECTS:A total of 7006 subjects aged 32-88 y with no
reported history of diabetes were included in the study.
RESULTS:For all subjects combined, increases in consumption of
ground-caffeinated coffee and caffeine at baseline were followed by
decreases in diabetes risk during follow-up. There were significant
statistical interactions between age and consumption of caffeine
(P=0.02) and ground-caffeinated coffee (P=0.03). Age-stratified
analysis showed that the decrease in diabetes risk only applied to
obtained for ground-decaffeinated coffee and regular tea. The
multivariate hazard ratio (HR) and 95% confidence interval for a 2
cups/day increment in the intake of ground-caffeinated coffee,
ground-decaffeinated coffee and regular tea was 0.86 (0.75-0.99), 0.58
(0.34-0.99) and 0.77 (0.59-1.00), respectively. The diabetes risk was
negatively related to the consumption in a dose-response manner. There
were strong statistical interactions between prior weight change and
beverage consumption for
Further analysis revealed that the decrease in diabetes risk only
applied to those who had lost weight, and that there was a positive
dose-response relationship between diabetes risk and weight change. For
example, the multivariate HR and 95% confidence interval for >0 vs 0
cups/day of ground-decaffeinated coffee was 0.17 (0.04-0.74), 0.52
(0.19-1.42), 0.77 (0.30-1.96) and 0.91 (0.39-2.14) for subgroups with
weight change of 20 lbs, respectively. There was
no significant association between diabetes risk and consumption of
instant-caffeinated coffee, instant-decaffeinated coffee or herbal tea.
Caffeine intake appeared to explain some, but not all, of the
diabetes-risk reduction and weight change.
CONCLUSION:The negative relationship between diabetes risk and
consumption of ground coffee and regular tea, observed for all NHEFS
subjects, actually only applied to nonelderly adults who had previously
lost weight.
Coffee, tea and diabetes: the role of weight loss and caffeine.
Greenberg JA, Axen KV, Schnoll R, Boozer CN.1Department of Health and
Nutrition Sciences, Brooklyn College of the City University of New
York, Brooklyn, NY, USA.International Journal of Obesity advance online
publication, 31 May 2005; doi:10.1038/sj.ijo.0802999.
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