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Obesity predisposes to caffeine toxicity? Obese diabetic dies after caffeine overdose
Obesity predisposes to caffeine toxicity? Obese diabetic dies after caffeine overdose -- Posted by I Jah Rastafari on 06-07-05 09:46
Caffeine is a mild central nervous stimulant that occurs naturally in
coffee beans, cocoa beans and tea leaves. In large doses, it can be
profoundly toxic, resulting in arrhythmia, tachycardia, vomiting,
convulsions, coma and death. The average cup of coffee or tea in the
United States is reported to contain between 40 and 150mg caffeine
although specialty coffees may contain much higher doses.
Over-the-counter supplements that are used to combat fatigue typically
contain 100-200mg caffeine per tablet and doses of 32-200mg are
included in a variety of prescription drug mixtures. Fatal caffeine
overdoses in adults are relatively rare and require the ingestion of a
large quantity of the drug, typically in excess of 5g. In this case,
femoral blood from a 29-year-old male with a history of obesity and
diabetes contained 567mg/L caffeine. The cause of death was ruled as
caffeine intoxication and the manner of death was accidental.
Forensic Sci Int. 2005 May 31;Fatal caffeine overdose: A case report.
Kerrigan S, Lindsey T. New Mexico Department of Health, Scientific
Laboratory Division, Toxicology Bureau, P.O. Box 4700, Albuquerque, NM
87196-4700, USA.
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