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Statin neuropathy masquerading as diabetic autoimmune polyneuropathy Re: Statin neuropathy masquerading as diabetic autoimmune polyneuropathy -- Posted by Jenny on 07-31-05 15:17
Ray wrote: > My priimary care giver had me on Zocor and tried to switch to Lipitor
> because it helps control the triglyceride levels better. Now I have severe
> neuropothy especially in feet to the point I can't feel anything on the skin
> area but those nerves sure can hurt.
>
> Since moving and locating a new doctor (Internal Medicines) he has taken my
> off statins and prescribed 10mg of Zetia. Triglycerides still are a concern
> but he suggest taking niacin to help with the battle. At present I have
> abnormal liver tests which was probably due to high amounts of Zocor and
> Ibuprophen. I tried and tried to lower the pain level by Ibuprophen (almost
> eating them like candy) has absolutely no effect on neuropothy pain.
>
> Ray O
>
>
Ray,
I initially had good results with Zetia, but after a few months I
developed persistent afterimages and extremely decreased libido and my
ophthalmologist suggested I stop the Zetia as it was all that was new in
my regimen. The afterimages got a lot better when I quit as did the libido.
Re: Statin neuropathy masquerading as diabetic autoimmune polyneuropathy -- Posted by Bill on 07-31-05 15:36
"Jenny" wrote in message
news:doednZgRU-Vt03DfRVn-sQ@rcn.net... > Ray wrote:
>> My priimary care giver had me on Zocor and tried to switch to Lipitor
>> because it helps control the triglyceride levels better. Now I have severe
>> neuropothy especially in feet to the point I can't feel anything on the
>> skin area but those nerves sure can hurt.
>>
>> Since moving and locating a new doctor (Internal Medicines) he has taken my
>> off statins and prescribed 10mg of Zetia. Triglycerides still are a
>> concern but he suggest taking niacin to help with the battle. At present I
>> have abnormal liver tests which was probably due to high amounts of Zocor
>> and Ibuprophen. I tried and tried to lower the pain level by Ibuprophen
>> (almost eating them like candy) has absolutely no effect on neuropothy
>> pain.
>>
>> Ray O
> Ray,
>
Note. 1. The statins may or may not be the problem. 2. Zetia and niacin MAY
(varies from person to person) have similar adverse effects as statins. If you
continue to have abnormal liver function tests, I suggest you discuss with
your Dr. stopping all of this. You may also wish to discuss alternative forms
of pain relief.
Bill
> I initially had good results with Zetia, but after a few months I developed
> persistent afterimages and extremely decreased libido and my ophthalmologist
> suggested I stop the Zetia as it was all that was new in my regimen. The
> afterimages got a lot better when I quit as did the libido.
Re: Statin neuropathy masquerading as diabetic autoimmune polyneuropathy -- Posted by Spram on 08-01-05 23:49
I went to see my doctor for my physical. He ordered tests and said that my
cholesterol was high. High Cholesterol runs in my family and all have very
long lives. My grandfather with cholesterol of 275 died at age 96. The
same goes for other family members. So he put me on Lipitor 10mg. I went
back every 2 months for tests. I have always had Reactive Hypoglycemia. My
FBS has always been on the low side. 75-85. After a full meal, my BS never
went over 120. What caused the reaction has always been heat. On a hot day
if I am outside doing anything stressfull, my BS will drop. I have measured
it as low as 62, cold sweats, shakes and a quick trip to the sugar jar and a
few teaspoons of sugar and a glass of orange juice and problem solved. On
trips, I always take hard candy in the glove box. Many in the family,
father, also like this. After 10 months of Lipitor 10mg. I had muscle
pains and tears (black and blue marks like I had been hit in that area),
vision changes, constant urination. So I went back to the Doctor who ran
tests and said I was Diabetic. No one had noticed that from the control
test of my FSB which was 79 and Glyco of 5.9 that day, that all the other
FSB tests had gone up but were still within the Normal Limits. That, is
very wrong. All tests are to be compared to the previous tests. Not just
look at the number and it is between 70-120 (now 70-115 so more people can
be labeled diabetic and the doctors and labs make more money) Well, on that
trip my FSB was 370 and GlycoHemoglobin was 17. Even after I had told him
of all the side effects to which he paid no attention, he said my
cholesterol was still high (did not drop one bit in 10 months with the diet
and Lipitor) and gave me a prescription for Lipitor 20mg and for Avandamet
1000/400 twice a day and Insulin injections. Pretty bad for someone who had
never been sick a day in his life. I called another Doctor whom I knew and
she said to immediately stop everything and go see her. She could not
believe what the other doctor had done. She said to take Niacin (Niacin has
always been known since the early 1950's to lower cholesterol) but to take
the flush free type and to stop the Lipitor immediately. That I was showing
the effects of evey Serious Side Effect of Lipitor and why the other doctor
could not see that was beyond comprehension. Well, that was one year ago
this past April. Today, my cholesterol is still high 220 with the Niacin
(used to be 270). My cardiologist performed a Cardiac Catherization and my
heart vessels are completely clean, no signs of any blockage whatsoever. My
age, early 50's and most important, my FSB is back to between 75-85 and my
Glyco is 5.8.
Had I done what the doctor had said, I would most likely be dead by now.
So, I prefer to live to a ripe old age as my other family members with my
high cholesterol than die from medications that I believe will someday be
taken off the market. The first Statin was taken off the market due to the
fact that it was killing people.
Also, it has never been proven that High Cholesterol causes heart disease in
100 percent of patients. 8 years ago the son of a Friend of Mine in
perfect health. Active jogger, ate no red meats, no fat diets, very low
cholesterol and normal blood pressure dropped dead from a Massive Heart
Attack while playing a game of racketball. He was 35 years old and left a
wife and 4 children ages 4-9.
6 months ago a good friend of the family had a severe heart attack. She is
an MD. The one who told me to stop the Lipitor. She is 49yrs, thin, walks
4 miles daily, basically 0 body fat, Cholesterol 95 Normal blood pressure
and a vegetarian.
So I will now continue with my life as usual. I have always been on the
heavy side but have never been one to eat sweets or too much red meat.
Chicken and Turkey are the mainstay of the meals at home. All with fresh
vegetables and diet pop.
Motto of my story, not all doctors listen to their patients. Many have the
"God" Syndrome. The doctor I went to is now facing the "Lawsuit" Syndrome
for the Hell he put me through and almost doing me in.
Everyone who has had problems with Lipitor or another Statin needs to file a
report with the FDA. I just received all my records from the control tests
to the one with the 370 FSB and already have the ones taken during the last
18 months with the normal readings. I will be sending everything to the FDA
(they want the test results to prove what you are telling them).
I know there are many others out there going through the same as I went
through or worse.
"Jenny" wrote in message
news:P-adnfMIZsSGA3bfRVn-jA@rcn.net... > Sharon Hope wrote:
> >
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16043768&query_hl=1 > >
> > Diabetes Care. 2005 Aug;28(8):2082.
> >
> > Statin neuropathy masquerading as diabetic autoimmune polyneuropathy.
> >
> > Vaughan TB, Bell DS.
> >
> > Division of Endocrinology, University of Alabama School of Medicine,
> > Faculty Office Tower, Suite 758, 510 20th St. S., Birmingham, AL 35294.
> > brooks@uab.edu.
> >
> > PMID: 16043768 [PubMed - in process]
> > Full text available via purchase or subscription from
>
> My board-certified endocrinologist told me she is seeing a lot of people
> with diabetes in very BAD shape from statins, and that taking them off
> the drugs makes a huge improvement in their pain and mental symptoms.
> She quoted one patient in her 60s who was suffering intense symptoms
> that turned out to be from statins as saying "you've given me my life
> back."
>
> My dad was put on statins in his 90s at a time when his mental abilities
> were 100% and immediately went into a significant physical and cognitive
> decline that ended in his death. The doctor insisted that the cause was
> an underlying heart condition. However, I found it very difficult to
> believe that the sudden mental deterioration that followed the statin
> prescription within a week or two was not due to the drug. My father
> also became very unsteady on his feet very soon after starting the
> statin and he died after hitting his head in a fall, not from heart
> disease.
>
> http://www.geocities.com/lottadata4u/dangerousdrugs.htm has pointers to
> several other medical studies pointing to the dangers of statins for
> older patients.
>
Re: Statin neuropathy masquerading as diabetic autoimmune polyneuropathy -- Posted by Jenny on 08-02-05 06:45
Spram wrote: > I went to see my doctor for my physical. He ordered tests and said that my
> cholesterol was high. High Cholesterol runs in my family and all have very
> long lives. My grandfather with cholesterol of 275 died at age 96.
Albert Einstein School of Medicine is conducting a study of people who
live to be 100 and one of their findings was that many of these people
have a cholesterol gene which gives them "large fluffy" LDL which
correlates with longevity. It also gives you very high cholesterol
readings.
My dad and I were subjects in that med school study, BTW, and I was
told that I have the same "longevity" gene.
In clearing out my dad's stuff after his death at age 100 (from a fall)
we found a 1970 doctor's report saying his cholesterol was 330. He never
took drugs for it until his mid90s. He did restrict calories, carbs,
fat, and salt.
Interestingly, my dad also seems to have inherited a Type 2 diabetes
gene not associated with obesity, as his mom died of diabetic kidney
disease, and several of his brothers had early heart attacks.
My dad gained a lot of weight in his 40s and went on an intense food
restriction diet which he stuck to for the next 55 years. It seems to
have controlled his blood sugar. Though he was diagnosed with heart
disease in his 70s and got a couple diabetic symptoms in his late 80s
(cataracts, macular problems) he only retired from his professional
career at 92 and made it to 99 with all his mental faculties intact. He
had a mild heart attack in his mid-90s and developed heart failure
afterwards, but he lived for another 4 years and died in his sleep 3
months after a fall in which he hit his head and developed unrelenting
brain bleeding.
I can't tell you happy I felt when I saw his 35 year old 330 cholesterol
reading. Mine hovers around 308 untreated (275 with metformin or low
carbing) and I've literally had doctors a) start screaming at me in the
office that I was committing suicide by refusing a statin and b) refuse
to have me as a patient unless I immediately went on a statin. I've had
terrible permanent side effects from common drugs and what I read about
the possible statin side effects (permanent cognitive problems) scared
me. My brain is about all that still works properly!
Re: Statin neuropathy masquerading as diabetic autoimmune polyneuropathy -- Posted by Spram on 08-04-05 00:26
Thank you for the info on that study, I am going to check on it. There is
longevity on my family, on both sides. My dad's family is the longest. Two
of his aunts (my great aunts) from Spain just recently died. One died two
years ago at the age of 104 and the remaining one died six months ago at the
age of 102. They lived in a farm in spain and their main diet of course
consisted of Fresh Milk, Read Meat (cows), Chicken, eggs, pork and of course
fresh lard to fry everything with. Their Cholesterol levels were over 300.
Dad is still alive, he is 83 and except for a mild heart attack (he smoked
until the heart attack) is doing fine. Mom is also alive 80 years of age
and both are still nonstop driving and going everywhere.
Mom's dad died 5 years ago at age 96 and it was due to complications of
gallbladder surgery. His heart was perfectly clean during the autopsy and
his diet were eggs fried in lard for breakfast, everything fried, red meats
basically the Spaniard Diet. He never changed his eating habits. Grandma,
mom's mom died at age 95 in her sleep 1 year after grandpa died. Autopsy
showed no actual cause of death. We think it was because she and granfather
were married when she was 17 and he 19. So after 78 years of marriage, one
could tell that she was not herself without him. Mom and dad are going the
same route, married so far 54 years. They basically knows what the other is
going to say before they open their mouths.
My cholesterol dropped some with the Niacin. But after trusting that doctor
and taking lipitor, NEVER AGAIN. If everything is fine why mess with it. I
still check my Blood sugar once a month. Just for peace of mind. Today, it
was 85, went up to 123 after dinner at 7pm. I just checked it now and it is
89. My Cholesterol hovers around 225 with the Niacin 500mg (non-flushing) 3
times a day. So like you, I experienced the worse side effects of Lipitor.
And now plan to stay just like I am.
I weigh between 205 and 240 depending on the time of year and that is
actually less than when I was in High School, many moons ago, where I
averaged 250. Even then my BS hovered between 75 and 85. The one thing
this doctor did not count on was on my having all the bloodwork that I have
ever had done. From surgery in high school to any other bloodwork for
physicals or other surgeries I have had. I also have copies of all X-Rays,
CT-Scans and MRI's done. Suprisingly, if you kindly ask the technician
doing the test, they will make copies. At the most, they charge a small
fee. But, having all those permanent records is worth the cost. And like I
said in the previous message, he upped the dose even after he saw all the
side effects I was having. Even when he saw the light you could say. He
still said "Lipitor does not cause an increase in blood sugar" To that I
told him, "read your PDR (Physicians Desk Reference - Big Thick Book, can be
found at the Library or bookstores sometimes) Right there it states that one
of the Serious Side Effects of Lipitor is a pathological increase in the
patients blood sugar" and in parenthesis is says "Diabetes" The previously
healthy doctor friend with LOW cholesterol, skinny, that I mentioned
previously said that she calls it and others call it "Lipitor (or Statin)
induced Hyperglycemia. What the statin does is block the insulin receptors
in the liver. So, you are producing Insulin, like I was doing, but the
liver does not sense it so it does not stop the sugar production. After the
statin has been taken for a long time, she said the damage will be
irreversible.
So just like you, until the day I die. NO STATINS. They can yell and
threaten all they want. I lived it first hand and have my family history to
rely on.
So again, thank your for the information. And best of Luck.
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